New Therapies for Age-Related Macular Degeneration
Christina Y. Weng, MD, MBA, Baylor College of Medicine, Houston, discussed therapies for macular degeneration.
CRISPR/Cas9 Shows Preclinical Efficacy in Fuchs Endothelial Corneal Dystrophy
Vision loss was prevented in a mouse model of Fuchs endothelial corneal dystrophy.
Understanding EYS Gene Mutations is Key to Retinitis Pigmentosa Treatment
Improved knowledge of the effects of mutations in the EYS gene may help inform new treatments.
AAV-Based Gene Therapy for Autoimmune Uveitis
A single-dose gene therapy for uveitis could fill an important treatment gap for patients.
Gene Therapy's Potential in Retinal Disease
A new animal model will facilitate the study and development of gene therapies in retinal diseases.
Gene Therapy Partially Restored Vision in Patient with Retinitis Pigmentosa
The Potential of CRISPR Therapies in Retinal Disorders
Targeted CRISPR therapy has potential in treating inherited retinal diseases.
AGTC-401, AGTC-402 Gene Therapies Well-Tolerated in Achromatopsia
Clinical trials for both AGTC-401 and AGTC-402 show promising results.
Changes in Photoreceptor Morphology Quantifiable Following Gene Therapy
Short-term morphological rescue was seen after voretigene neparvovec-rzyl treatment.
ADVM-022 is Efficacious and Durable in nAMD With Single Injection
The OPTIC phase 1 study showed that the treatment was associated with a significant reduction in treatment burden after 1 injection.
Imaging End Points a Good Indicator of Therapeutic Response in Retinitis Pigmentosa
Optical coherence tomography characteristics may be predictive of the efficacy of intravitreal injection of allogeneic human retinal progenitor cells, according to research presented at ARVO 2021.