Pushing for a New Era in Cardiology: Matt Killeen, PhD

Commentary
Video

Matt Killeen, PhD, chief scientific officer at Renovacor, shares updates on the company's lead candidate, REN-001, an adeno-associated viral vector serotype 9-based gene therapy for the treatment of BAG3-associated dilated cardiomyopathy.

"Given the fact that today's therapies for heart failure and inherited heart diseases really just work around the edges, patients can quickly find themselves exhausting current treatment options and facing the prospect of procedures." —Matt Killeen, PhD, Chief Scientific Officer, Renovacor

As more and more patients become empowered to take control of their individual health, there is increasing emphasis on cardiac screening and genetic testing. One form of genetically driven heart failure, BAG3-associated dilated cardiomyopathy (DCM), has become an area of focus, as there are currently no commercially available targeted treatments.

Researchers at Renovacor are hoping to change that with REN-001, an adeno-associated viral (AAV) vector serotype 9-based gene therapy for the treatment of DCM.

Matt Killeen, PhD, chief scientific officer at Renovacor, joins CGTL to share updates on REN-001, which is in late stage preclinical development, and other candidates in the pipeline, as well as to shed some light on why the company chose to focus on this genetic form of heart disease.

Related Videos
Faraz Ali, MBA, the chief executive officer of Tenaya Therapeutics
Faraz Ali, MBA, the chief executive officer of Tenaya Therapeutics
Evan Weber, PhD, an assistant professor of pediatrics at Children's Hospital of Philadelphia
Faraz Ali, MBA, the chief executive officer of Tenaya Therapeutics
Shankar Ramaswamy, MD, the cofounder, chairman, and CEO of Kriya Therapeutics
Kevin Campbell, PhD, a Howard Hughes Investigator at the University of Iowa
Debora Mazzetti, MS, on Multitargeting MicroRNA in Glioblastoma
Abhishek Gupta, BS, the senior vice president of genetic medicines at Syneos Health
Francesca Del Bufalo, MD, PhD, a medical doctor and scientist at Bambino Gesù Chidren’s Hospital
Luke Roberts, MBBS, PhD, on Early Clinical Data on Congestive Heart Failure Gene Therapy
© 2024 MJH Life Sciences

All rights reserved.